Vocab Bloom Hub

secretase

/sɪˈkriː.teɪz/

Tradução: Enzima que cliva proteínas transmembrana, como a proteína precursora amiloide, liberando fragmentos que podem formar placas amiloides no cérebro, um achado característico da doença de Alzheimer.

1 verbete

noun

/sɪˈkriː.teɪz/C2formalmedical
  • ptEnzima que cliva proteínas transmembrana, como a proteína precursora amiloide, liberando fragmentos que podem formar placas amiloides no cérebro, um achado característico da doença de Alzheimer.

A set of enzymes that cleave a longer protein into fragments, producing amyloid protein pieces that aggregate into plaques in brain tissue, a key pathological feature of Alzheimer's disease.

  1. Enzyme involved in Alzheimer's diseaseC2formalmedical

    A type of enzyme that cuts a larger protein into smaller fragments, including amyloid beta peptides, which can accumulate in the brain and form plaques associated with Alzheimer's disease.

    ptEnzima envolvida na doença de Alzheimer

    • Researchers are studying how secretase activity contributes to plaque formation.
    • Inhibitors of secretase are being tested as potential treatments for Alzheimer's.
    • The enzyme secretase plays a key role in the production of amyloid beta.